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Separating planar cell polarity and Hippo pathway activities of the protocadherins Fat and Dachsous
The giant Drosophila protocadherin Fat (Ft) affects planar cell polarity (PCP). Ft also inhibits the overgrowth of imaginal discs via the Hippo pathway, repressing the activity of the transcription co-factor Yorkie (Yki). Much of Ft activity is likely to be mediated by its intracellular domain (Ft I...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308182/ https://ncbi.nlm.nih.gov/pubmed/22399682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.070367 |
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