Separating planar cell polarity and Hippo pathway activities of the protocadherins Fat and Dachsous

The giant Drosophila protocadherin Fat (Ft) affects planar cell polarity (PCP). Ft also inhibits the overgrowth of imaginal discs via the Hippo pathway, repressing the activity of the transcription co-factor Yorkie (Yki). Much of Ft activity is likely to be mediated by its intracellular domain (Ft I...

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Bibliographic Details
Main Authors: Matakatsu, Hitoshi, Blair, Seth S.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2012
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308182/
https://ncbi.nlm.nih.gov/pubmed/22399682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.070367
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