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Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling

Nutritional excess and hyperlipidemia increase the heart’s susceptibility to ischemic injury. Mammalian target of rapamycin (mTOR) controls the cellular response to nutritional status and may play a role in ischemic injury. To explore the effect of hypercholesterolemia on cardiac mTOR signaling, we...

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Bibliografski detalji
Glavni autori: Glazer, Hilary P., Osipov, Robert M., Clements, Richard T., Sellke, Frank W., Bianchi, Cesario
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308015/
https://ncbi.nlm.nih.gov/pubmed/19395857
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