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Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling

Nutritional excess and hyperlipidemia increase the heart’s susceptibility to ischemic injury. Mammalian target of rapamycin (mTOR) controls the cellular response to nutritional status and may play a role in ischemic injury. To explore the effect of hypercholesterolemia on cardiac mTOR signaling, we...

詳細記述

保存先:
書誌詳細
主要な著者: Glazer, Hilary P., Osipov, Robert M., Clements, Richard T., Sellke, Frank W., Bianchi, Cesario
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308015/
https://ncbi.nlm.nih.gov/pubmed/19395857
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