Macrophage Killing of Bacterial and Fungal Pathogens Is Not Inhibited by Intense Intracellular Accumulation of the Lipoglycopeptide Antibiotic Oritavancin

Intact phagocytic effector function is fundamental to host defense against microbial pathogens. Concern has been raised regarding the potential that accumulation of certain agents, including cationic amphiphilic antibiotics, within macrophages could cause a mixed-lipid storage disorder, resulting in...

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Hauptverfasser: Baquir, Beverlie, Lemaire, Sandrine, Van Bambeke, Françoise, Tulkens, Paul M., Lin, Lin, Spellberg, Brad
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
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Supplement Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307583/
https://ncbi.nlm.nih.gov/pubmed/22431853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cir921
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