Mixed-Lipid Storage Disorder Induced in Macrophages and Fibroblasts by Oritavancin (LY333328), a New Glycopeptide Antibiotic with Exceptional Cellular Accumulation

Oritavancin, a semisynthetic derivative of vancomycin endowed with a cationic amphiphilic character, accumulates to large extent in the lysosomes of eukaryotic cells (F. Van Bambeke, S. Carryn, C. Seral, H. Chanteux, D. Tyteca, M. P. Mingeot-Leclercq, and P. M. Tulkens, Antimicrob. Agents Chemother....

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Detalles Bibliográficos
Main Authors: Van Bambeke, Françoise, Saffran, Jennifer, Mingeot-Leclercq, Marie-Paule, Tulkens, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087646/
https://ncbi.nlm.nih.gov/pubmed/15855483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.1695-1700.2005
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