Tannic Acid Is a Natural β-Secretase Inhibitor That Prevents Cognitive Impairment and Mitigates Alzheimer-like Pathology in Transgenic Mice

Amyloid precursor protein (APP) proteolysis is essential for production of amyloid-β (Aβ) peptides that form β-amyloid plaques in brains of Alzheimer disease (AD) patients. Recent focus has been directed toward a group of naturally occurring anti-amyloidogenic polyphenols known as flavonoids. We ora...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Mori, Takashi, Rezai-Zadeh, Kavon, Koyama, Naoki, Arendash, Gary W., Yamaguchi, Haruyasu, Kakuda, Nobuto, Horikoshi-Sakuraba, Yuko, Tan, Jun, Town, Terrence
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307267/
https://ncbi.nlm.nih.gov/pubmed/22219198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.294025
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars