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Overexpression of Human S100B Exacerbates Cerebral Amyloidosis and Gliosis in the Tg2576 Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common progressive dementia and is pathologically characterized by brain deposition of amyloid-β (Aβ) peptide as senile plaques. Inflammatory and immune response pathways are chronically activated in AD patient brains at low levels, and likely play a role in dise...

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Detalhes bibliográficos
Main Authors: MORI, TAKASHI, KOYAMA, NAOKI, ARENDASH, GARY W., HORIKOSHI-SAKURABA, YUKO, TAN, JUN, TOWN, TERRENCE
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795105/
https://ncbi.nlm.nih.gov/pubmed/19705461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20924
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