Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma

A genome-wide screen for genetic alterations in radiation-induced thymic lymphomas generated from p53+/− and p53−/− mice showed frequent loss of heterozygosity (LOH) on chromosome 6. Fine mapping of these LOH regions revealed three non-overlapping regions, one of which was refined to a 0.2 Mb interv...

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Detalhes bibliográficos
Main Authors: Mao, J-H, Wu, D, Kim, I-J, Kang, H C, Wei, G, Climent, J, Kumar, A, Pelorosso, F G, DelRosario, R, Huang, E J, Balmain, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307058/
https://ncbi.nlm.nih.gov/pubmed/21785465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.306
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