STRUCTURE OF THE EGF RECEPTOR TRANSACTIVATION CIRCUIT INTEGRATES MULTIPLE SIGNALS WITH CELL CONTEXT

Transactivation of the epidermal growth factor receptor (EGFR) is thought to be a process by which a variety of cellular inputs can be integrated into a single signaling pathway through either stimulated proteolysis (shedding) of membrane-anchored EGFR ligands or by modification of the activity of t...

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Main Authors: Joslin, Elizabeth J., Shankaran, Harish, Opresko, Lee K., Bollinger, Nikki, Lauffenburger, Douglas A., Wiley, H. Steven
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306786/
https://ncbi.nlm.nih.gov/pubmed/20458382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c003921g
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