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Self-Organization of Polarized Cell Signaling via Autocrine Circuits: Computational Model Analysis

Recent studies have suggested that autocrine signaling through epidermal growth factor receptor (EGFR) might be involved in generating or maintaining an intrinsic polarity in tissue cells, possibly via spatial localization of EGFR-mediated signaling. The difficulty of experimental investigation of a...

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Detalhes bibliográficos
Main Authors: Maly, Ivan V., Wiley, H. Steven, Lauffenburger, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303773/
https://ncbi.nlm.nih.gov/pubmed/14695245
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