Ligand Accumulation in Autocrine Cell Cultures

Cell-culture assays are routinely used to analyze autocrine signaling systems, but quantitative experiments are rarely possible. To enable the quantitative design and analysis of experiments with autocrine cells, we develop a biophysical theory of ligand accumulation in cell-culture assays. Our theo...

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Bibliographic Details
Main Authors: Monine, Michael I., Berezhkovskii, Alexander M., Joslin, Elizabeth J., Wiley, H. Steven, Lauffenburger, Douglas A., Shvartsman, Stanislav Y.
Format: Artigo
Language:Inglês
Published: Biophysical Society 2005
Subjects:
Biophysical Theory and Modeling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305338/
https://ncbi.nlm.nih.gov/pubmed/15653719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051425
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