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Self-Organization of Polarized Cell Signaling via Autocrine Circuits: Computational Model Analysis

Recent studies have suggested that autocrine signaling through epidermal growth factor receptor (EGFR) might be involved in generating or maintaining an intrinsic polarity in tissue cells, possibly via spatial localization of EGFR-mediated signaling. The difficulty of experimental investigation of a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Maly, Ivan V., Wiley, H. Steven, Lauffenburger, Douglas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303773/
https://ncbi.nlm.nih.gov/pubmed/14695245
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