Real-time quantitative measurement of autocrine ligand binding indicates that autocrine loops are spatially localized

Autocrine ligands are important regulators of many normal tissues and have been implicated in a number of disease states, including cancer. However, because by definition autocrine ligands are synthesized, secreted, and bound to cell receptors within an intrinsically self-contained “loop,” standard...

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Detaylı Bibliyografya
Asıl Yazarlar: Lauffenburger, Douglas A., Oehrtman, Gregory T., Walker, Laura, Wiley, H. Steven
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1998
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC28049/
https://ncbi.nlm.nih.gov/pubmed/9860975
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