Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor

Although the ERK pathway has a central role in the response of cells to growth factors, its regulatory structure and dynamics are incompletely understood. To investigate ERK activation in real time, we expressed an ERK–GFP fusion protein in human mammary epithelial cells. On EGF stimulation, we obse...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shankaran, Harish, Ippolito, Danielle L, Chrisler, William B, Resat, Haluk, Bollinger, Nikki, Opresko, Lee K, Wiley, H Steven
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824491/
https://ncbi.nlm.nih.gov/pubmed/19953086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.90
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