Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor

Although the ERK pathway has a central role in the response of cells to growth factors, its regulatory structure and dynamics are incompletely understood. To investigate ERK activation in real time, we expressed an ERK–GFP fusion protein in human mammary epithelial cells. On EGF stimulation, we obse...

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Detaylı Bibliyografya
Asıl Yazarlar: Shankaran, Harish, Ippolito, Danielle L, Chrisler, William B, Resat, Haluk, Bollinger, Nikki, Opresko, Lee K, Wiley, H Steven
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824491/
https://ncbi.nlm.nih.gov/pubmed/19953086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.90
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