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Toward understanding Machado-Joseph Disease

Machado-Joseph disease (MJD), also known as Spinocerebellar ataxia type 3 (SCA3), is the most common inherited spinocerebellar ataxia and one of many polyglutamine neurodegenerative diseases. In MJD, a CAG repeat expansion encodes an abnormally long polyglutamine (polyQ) tract in the disease protein...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Costa, Maria do Carmo, Paulson, Henry L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306771/
https://ncbi.nlm.nih.gov/pubmed/22133674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2011.11.006
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