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Compromised Mitochondrial Complex II in Models of Machado-Joseph Disease
Machado-Joseph disease (MJD), also known as Spinocerebellar Ataxia type 3, is an inherited dominant autosomal neurodegenerative disorder. An expansion of CAG repeats in the ATXN3 gene is translated as an expanded polyglutamine domain in the disease protein, ataxin-3. Selective neurodegeneration in M...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338188/ https://ncbi.nlm.nih.gov/pubmed/22037589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2011.10.010 |
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