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Two copies of the SecY channel and acidic lipids are necessary to activate the SecA translocation ATPase

The SecA ATPase associates with the SecY complex to push preproteins across the bacterial membrane. Because a single SecY is sufficient to create the conducting channel, the function of SecY oligomerization remains unclear. Here, we have analyzed the translocation reaction using nanodiscs. We show t...

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Detalhes bibliográficos
Main Authors: Dalal, Kush, Chan, Catherine S., Sligar, Stephen G., Duong, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306715/
https://ncbi.nlm.nih.gov/pubmed/22378651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117783109
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