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Two copies of the SecY channel and acidic lipids are necessary to activate the SecA translocation ATPase
The SecA ATPase associates with the SecY complex to push preproteins across the bacterial membrane. Because a single SecY is sufficient to create the conducting channel, the function of SecY oligomerization remains unclear. Here, we have analyzed the translocation reaction using nanodiscs. We show t...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306715/ https://ncbi.nlm.nih.gov/pubmed/22378651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117783109 |
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