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Two copies of the SecY channel and acidic lipids are necessary to activate the SecA translocation ATPase
The SecA ATPase associates with the SecY complex to push preproteins across the bacterial membrane. Because a single SecY is sufficient to create the conducting channel, the function of SecY oligomerization remains unclear. Here, we have analyzed the translocation reaction using nanodiscs. We show t...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306715/ https://ncbi.nlm.nih.gov/pubmed/22378651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117783109 |
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