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Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation
Multimodular polyketide synthases (PKSs) have an assembly line architecture in which a set of protein domains, known as a module, participates in one round of polyketide chain elongation and associated chemical modifications, after which the growing chain is translocated to the next PKS module. The...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306671/ https://ncbi.nlm.nih.gov/pubmed/22371562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118734109 |
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