N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis

Wnt signalling has pivotal roles in tumour progression and metastasis; however, the exact molecular mechanism of Wnt signalling in the metastatic process is as yet poorly defined. Here we demonstrate that the tumour metastasis suppressor gene, NDRG1, interacts with the Wnt receptor, LRP6, followed b...

詳細記述

保存先:
書誌詳細
主要な著者: Liu, Wen, Xing, Fei, Iiizumi-Gairani, Megumi, Okuda, Hiroshi, Watabe, Misako, Pai, Sudha K, Pandey, Puspa R, Hirota, Shigeru, Kobayashi, Aya, Mo, Yin-Yuan, Fukuda, Koji, Li, Yi, Watabe, Kounosuke
フォーマット: Artigo
言語:Inglês
出版事項: WILEY-VCH Verlag 2012
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306556/
https://ncbi.nlm.nih.gov/pubmed/22246988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100190
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