N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis

Wnt signalling has pivotal roles in tumour progression and metastasis; however, the exact molecular mechanism of Wnt signalling in the metastatic process is as yet poorly defined. Here we demonstrate that the tumour metastasis suppressor gene, NDRG1, interacts with the Wnt receptor, LRP6, followed b...

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Autors principals: Liu, Wen, Xing, Fei, Iiizumi-Gairani, Megumi, Okuda, Hiroshi, Watabe, Misako, Pai, Sudha K, Pandey, Puspa R, Hirota, Shigeru, Kobayashi, Aya, Mo, Yin-Yuan, Fukuda, Koji, Li, Yi, Watabe, Kounosuke
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2012
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306556/
https://ncbi.nlm.nih.gov/pubmed/22246988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100190
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