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N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis

Wnt signalling has pivotal roles in tumour progression and metastasis; however, the exact molecular mechanism of Wnt signalling in the metastatic process is as yet poorly defined. Here we demonstrate that the tumour metastasis suppressor gene, NDRG1, interacts with the Wnt receptor, LRP6, followed b...

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מידע ביבליוגרפי
Main Authors: Liu, Wen, Xing, Fei, Iiizumi-Gairani, Megumi, Okuda, Hiroshi, Watabe, Misako, Pai, Sudha K, Pandey, Puspa R, Hirota, Shigeru, Kobayashi, Aya, Mo, Yin-Yuan, Fukuda, Koji, Li, Yi, Watabe, Kounosuke
פורמט: Artigo
שפה:Inglês
יצא לאור: WILEY-VCH Verlag 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306556/
https://ncbi.nlm.nih.gov/pubmed/22246988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100190
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