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Expression and Characterization of Drosophila Signal Peptide Peptidase-Like (sppL), a Gene That Encodes an Intramembrane Protease

Intramembrane proteases of the Signal Peptide Peptidase (SPP) family play important roles in developmental, metabolic and signaling pathways. Although vertebrates have one SPP and four SPP-like (SPPL) genes, we found that insect genomes encode one Spp and one SppL. Characterization of the Drosophila...

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Autors principals: Casso, David J., Liu, Songmei, Biehs, Brian, Kornberg, Thomas B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306293/
https://ncbi.nlm.nih.gov/pubmed/22439002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033827
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