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Drosophila Signal Peptide Peptidase Is an Essential Protease for Larval Development

We identified the Drosophila melanogaster Signal peptide peptidase gene (Spp) that encodes a multipass transmembrane aspartyl protease. Drosophila SPP is homologous to the human signal peptide peptidase (SPP) and is distantly related to the presenilins. We show that, like human SPP, Drosophila SPP c...

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Detaylı Bibliyografya
Asıl Yazarlar: Casso, David J., Tanda, Soichi, Biehs, Brian, Martoglio, Bruno, Kornberg, Thomas B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449732/
https://ncbi.nlm.nih.gov/pubmed/15716490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.039933
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