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Expression and Characterization of Drosophila Signal Peptide Peptidase-Like (sppL), a Gene That Encodes an Intramembrane Protease

Intramembrane proteases of the Signal Peptide Peptidase (SPP) family play important roles in developmental, metabolic and signaling pathways. Although vertebrates have one SPP and four SPP-like (SPPL) genes, we found that insect genomes encode one Spp and one SppL. Characterization of the Drosophila...

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Detalhes bibliográficos
Main Authors: Casso, David J., Liu, Songmei, Biehs, Brian, Kornberg, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306293/
https://ncbi.nlm.nih.gov/pubmed/22439002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033827
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