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Novel Binding Mode of a Potent and Selective Tankyrase Inhibitor
Tankyrases (TNKS1 and TNKS2) are key regulators of cellular processes such as telomere pathway and Wnt signaling. IWRs (inhibitors of Wnt response) have recently been identified as potent and selective inhibitors of tankyrases. However, it is not clear how these IWRs interact with tankyrases. Here w...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306292/ https://ncbi.nlm.nih.gov/pubmed/22438990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033740 |
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