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Novel Binding Mode of a Potent and Selective Tankyrase Inhibitor
Tankyrases (TNKS1 and TNKS2) are key regulators of cellular processes such as telomere pathway and Wnt signaling. IWRs (inhibitors of Wnt response) have recently been identified as potent and selective inhibitors of tankyrases. However, it is not clear how these IWRs interact with tankyrases. Here w...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306292/ https://ncbi.nlm.nih.gov/pubmed/22438990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033740 |
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