Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode

অনুরূপ উপাদানগুলি

• Irreversible inhibition of BTK kinase by a novel highly selective inhibitor CHMFL-BTK-11 suppresses inflammatory response in rheumatoid arthritis model
  অনুযায়ী: Wu, Hong, অন্যান্য
  প্রকাশিত: (2017)
• Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML)
  অনুযায়ী: Wu, Jiaxin, অন্যান্য
  প্রকাশিত: (2019)
• Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML)
  অনুযায়ী: Liu, Feiyang, অন্যান্য
  প্রকাশিত: (2016)
• Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells
  অনুযায়ী: Wu, Hong, অন্যান্য
  প্রকাশিত: (2015)
• Discovery of a highly selective VEGFR2 kinase inhibitor CHMFL-VEGFR2-002 as a novel anti-angiogenesis agent
  অনুযায়ী: Zongru Jiang, অন্যান্য
  প্রকাশিত: (2020-03-01)