Merlin/NF2 Regulates Angiogenesis in Schwannomas through a Rac1/Semaphorin 3F-Dependent Mechanism

Neurofibromatosis type 2 (NF2) is an autosomal-dominant multiple neoplasia syndrome that results from mutations in the NF2 tumor suppressor gene. Patients with NF2 develop hallmark schwannomas that require surgery or radiation, both of which have significant adverse effects. Recent studies have indi...

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Détails bibliographiques
Auteurs principaux: Wong, Hon-Kit, Shimizu, Akio, Kirkpatrick, Nathaniel D, Garkavtsev, Igor, Chan, Annie W, di Tomaso, Emmanuelle, Klagsbrun, Michael, Jain, Rakesh K
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press Inc. 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306254/
https://ncbi.nlm.nih.gov/pubmed/22431917
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