Merlin/NF2 Regulates Angiogenesis in Schwannomas through a Rac1/Semaphorin 3F-Dependent Mechanism

Neurofibromatosis type 2 (NF2) is an autosomal-dominant multiple neoplasia syndrome that results from mutations in the NF2 tumor suppressor gene. Patients with NF2 develop hallmark schwannomas that require surgery or radiation, both of which have significant adverse effects. Recent studies have indi...

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Detalhes bibliográficos
Main Authors: Wong, Hon-Kit, Shimizu, Akio, Kirkpatrick, Nathaniel D, Garkavtsev, Igor, Chan, Annie W, di Tomaso, Emmanuelle, Klagsbrun, Michael, Jain, Rakesh K
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306254/
https://ncbi.nlm.nih.gov/pubmed/22431917
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