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Hypoxia induces tumor and endothelial cell migration in a Semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor Neuropilin 2

Neuropilin-2 (NRP2) is a receptor expressed by tumor cells and endothelial cells (EC) that binds both semaphorin 3F (SEMA3F), a potent inhibitor of tumor angiogenesis and metastasis, and vascular endothelial growth factor (VEGF), a potent stimulator of tumor angiogenesis. It was found that glioblast...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Coma, Silvia, Shimizu, Akio, Klagsbrun, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210211/
https://ncbi.nlm.nih.gov/pubmed/21610314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.5.3.16294
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