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Synoviocyte innate immune responses: TANK-binding kinase-1 as a potential therapeutic target in rheumatoid arthritis

Objectives. Innate immune responses in the rheumatoid synovium contribute to inflammation and joint destruction in RA. Two IκB kinase (IKK)-related kinases, TNF receptor associated factor (TRAF) family member-associated nuclear factor κ-light-chain enhancer of activated B cells (NF-κB) activator (TA...

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Detalhes bibliográficos
Main Authors: Hammaker, Deepa, Boyle, David L., Firestein, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306173/
https://ncbi.nlm.nih.gov/pubmed/21613249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/ker154
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