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Efficient trans-activation by the HIV-2 Tat protein requires a duplicated TAR RNA structure.

Human immunodeficiency viruses HIV-1 and HIV-2 encode a Tat protein that activates transcription from the long terminal repeats. The target for transactivation is termed the trans-acting responsive (TAR) element. TAR has an extensively folded RNA secondary structure and is present at the 5' end...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Berkhout, B, Gatignol, A, Silver, J, Jeang, K T
Format: Artigo
Language:Inglês
Published: Oxford University Press 1990
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330604/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2186367/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.7.1839
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