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Efficient trans-activation by the HIV-2 Tat protein requires a duplicated TAR RNA structure.

Human immunodeficiency viruses HIV-1 and HIV-2 encode a Tat protein that activates transcription from the long terminal repeats. The target for transactivation is termed the trans-acting responsive (TAR) element. TAR has an extensively folded RNA secondary structure and is present at the 5' end...

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Detalhes bibliográficos
Main Authors: Berkhout, B, Gatignol, A, Silver, J, Jeang, K T
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC330604/
https://ncbi.nlm.nih.gov/pubmed/2186367
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