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Assignment of Backbone Resonances in a Eukaryotic Protein Kinase – ERK2 as an Illustrative Example

A first step towards the analysis of the structure, dynamics and interactions of proteins by NMR is obtaining an acceptable level of resonance assignments. This process is non-trivial in most eukaryotic kinases given their size and sub-optimal behavior in solution. Using inactive ERK2 as a represent...

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Bibliographic Details
Main Authors: Piserchio, Andrea, Dalby, Kevin N., Ghose, Ranajeet
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305997/
https://ncbi.nlm.nih.gov/pubmed/22167683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-480-3_19
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