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Assignment of Backbone Resonances in a Eukaryotic Protein Kinase – ERK2 as an Illustrative Example
A first step towards the analysis of the structure, dynamics and interactions of proteins by NMR is obtaining an acceptable level of resonance assignments. This process is non-trivial in most eukaryotic kinases given their size and sub-optimal behavior in solution. Using inactive ERK2 as a represent...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3305997/ https://ncbi.nlm.nih.gov/pubmed/22167683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-480-3_19 |
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