Mutation analysis of BRAF and KIT in circulating melanoma cells at the single cell level

BACKGROUND: The availability of molecular-targeted therapies for the treatment of melanoma has emphasised the need to identify mutations in target genes such as BRAF and KIT. Circulating tumour cells (CTC) are present in the peripheral blood of a significant proportion of cancer patients. METHODS: H...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sakaizawa, K, Goto, Y, Kiniwa, Y, Uchiyama, A, Harada, K, Shimada, S, Saida, T, Ferrone, S, Takata, M, Uhara, H, Okuyama, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Molecular Diagnostics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305957/
https://ncbi.nlm.nih.gov/pubmed/22281663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.12
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