Mutation analysis of BRAF and KIT in circulating melanoma cells at the single cell level

BACKGROUND: The availability of molecular-targeted therapies for the treatment of melanoma has emphasised the need to identify mutations in target genes such as BRAF and KIT. Circulating tumour cells (CTC) are present in the peripheral blood of a significant proportion of cancer patients. METHODS: H...

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Bibliografiska uppgifter
Huvudupphovsmän: Sakaizawa, K, Goto, Y, Kiniwa, Y, Uchiyama, A, Harada, K, Shimada, S, Saida, T, Ferrone, S, Takata, M, Uhara, H, Okuyama, R
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2012
Ämnen:
Molecular Diagnostics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305957/
https://ncbi.nlm.nih.gov/pubmed/22281663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.12
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