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Polyclonality of BRAF Mutations in Acquired Melanocytic Nevi

Melanocytic nevi are thought to be senescent clones of melanocytes that have acquired an oncogenic BRAF mutation. BRAF mutation is considered to be a crucial step in the initiation of melanocyte transformation. However, using immunomagnetic separation or laser-capture microdissection, we examined BR...

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Hlavní autoři: Lin, Jingrong, Takata, Minoru, Murata, Hiroshi, Goto, Yasufumi, Kido, Kenji, Ferrone, Soldano, Saida, Toshiaki
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765260/
https://ncbi.nlm.nih.gov/pubmed/19752400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djp309
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