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Polyclonality of BRAF Mutations in Acquired Melanocytic Nevi

Melanocytic nevi are thought to be senescent clones of melanocytes that have acquired an oncogenic BRAF mutation. BRAF mutation is considered to be a crucial step in the initiation of melanocyte transformation. However, using immunomagnetic separation or laser-capture microdissection, we examined BR...

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Main Authors: Lin, Jingrong, Takata, Minoru, Murata, Hiroshi, Goto, Yasufumi, Kido, Kenji, Ferrone, Soldano, Saida, Toshiaki
格式: Artigo
語言:Inglês
出版: Oxford University Press 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765260/
https://ncbi.nlm.nih.gov/pubmed/19752400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djp309
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