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Inhibition of glycogen synthase kinase 3β prevents NSAID-induced acute kidney injury
Clinical use of non-steroidal anti-inflammatory drugs (NSAIDs) like diclofenac (DCLF) is limited by multiple adverse effects, including renal toxicity leading to acute kidney injury. In mice with DCLF-induced nephrotoxicity TDZD-8, a selective glycogen synthase kinase (GSK)3β inhibitor, improved acu...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3305839/ https://ncbi.nlm.nih.gov/pubmed/22258319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.443 |
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