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Conformational Control of the Binding of the Transactivation Domain of the MLL Protein and c-Myb to the KIX Domain of CREB

The KIX domain of CBP is a transcriptional coactivator. Concomitant binding to the activation domain of proto-oncogene protein c-Myb and the transactivation domain of the trithorax group protein mixed lineage leukemia (MLL) transcription factor lead to the biologically active ternary MLL∶KIX∶c-Myb c...

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Bibliografiske detaljer
Main Authors: Korkmaz, Elif Nihal, Nussinov, Ruth, Haliloğlu, Türkan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305381/
https://ncbi.nlm.nih.gov/pubmed/22438798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002420
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