Conformational Control of the Binding of the Transactivation Domain of the MLL Protein and c-Myb to the KIX Domain of CREB

The KIX domain of CBP is a transcriptional coactivator. Concomitant binding to the activation domain of proto-oncogene protein c-Myb and the transactivation domain of the trithorax group protein mixed lineage leukemia (MLL) transcription factor lead to the biologically active ternary MLL∶KIX∶c-Myb c...

Full description

Saved in:
Bibliographic Details
Main Authors: Korkmaz, Elif Nihal, Nussinov, Ruth, Haliloğlu, Türkan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305381/
https://ncbi.nlm.nih.gov/pubmed/22438798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002420
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items