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Insights into the structure and activity of prototype foamy virus RNase H

BACKGROUND: RNase H is an endonuclease that hydrolyzes the RNA strand in RNA/DNA hybrids. Retroviral reverse transcriptases harbor a C-terminal RNase H domain whose activity is essential for viral replication. The RNase H degrades the viral genomic RNA after the first DNA strand is synthesized. Here...

詳細記述

保存先:
書誌詳細
主要な著者: Leo, Berit, Hartl, Maximilian J, Schweimer, Kristian, Mayr, Florian, Wöhrl, Birgitta M
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305377/
https://ncbi.nlm.nih.gov/pubmed/22325739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-14
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