Perturbation of DNA hairpins containing the EcoRI recognition site by hairpin loops of varying size and composition: physical (NMR and UV) and enzymatic (EcoRI) studies.

We have investigated loop-induced structural perturbation of the stem structure in hairpins d(GAATTCXnGAATTC) (X = A, T and n = 3, 4, 5 and 6) that contain an EcoRI restriction site in close proximity to the hairpin loop. Oligonucleotides containing either a T3 or a A3 loop were not hydrolyzed by th...

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Dettagli Bibliografici

Pubblicato in:	Nucleic Acids Res
Autori principali:	Germann, M W, Kalisch, B W, Lundberg, P, Vogel, H J, van de Sande, J H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1990
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330516/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2326190/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.6.1489
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