Therapeutic implications of targeting the PI3Kinase/AKT/mTOR signaling module in melanoma therapy

The PI3Kinase/AKT/mTOR signaling module is implicated in various cellular functions including cell survival, growth and proliferation, glucose metabolism, apoptosis, migration, and angiogenesis. Increased expression of AKT and its up- and downstream regulators is linked to several types of cancer. A...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Jazirehi, Ali R, Wenn, Peter B, Damavand, Mohsen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: e-Century Publishing Corporation 2012
Konular:
Review Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304564/
https://ncbi.nlm.nih.gov/pubmed/22485197
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