Phenformin as prophylaxis and therapy in breast cancer xenografts

BACKGROUND: Observations that diabetics treated with biguanide drugs have a reduced risk of developing cancer have prompted an enthusiasm for these agents as anti-cancer therapies. We sought to determine the efficacy of the biguanide phenformin in the chemoprophylaxis and in the treatment of oestrog...

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Autors principals: Appleyard, M V C L, Murray, K E, Coates, P J, Wullschleger, S, Bray, S E, Kernohan, N M, Fleming, S, Alessi, D R, Thompson, A M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Translational Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304424/
https://ncbi.nlm.nih.gov/pubmed/22361631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.56
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