Cyclooxygenase-2 inhibition: effects on tumour growth, cell cycling and lymphangiogenesis in a xenograft model of breast cancer

Cyclooxygenase-2 (COX-2) is associated with poor-prognosis breast cancer. We used a nude mouse xenograft model to determine the effects of COX-2 inhibition in breast cancer. Oestrogen receptor (ER)-positive MCF7/HER2-18 and ER-negative MDAMB231 breast cancer cell lines were injected into nude mice a...

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Detalhes bibliográficos
Main Authors: Barnes, N L P, Warnberg, F, Farnie, G, White, D, Jiang, W, Anderson, E, Bundred, N J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360050/
https://ncbi.nlm.nih.gov/pubmed/17285134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603593
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