Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy

BACKGROUND: Autophagy allows recycling of cellular components and may facilitate cell survival after chemotherapy. Pantoprazole inhibits proton pumps and is reported to inhibit autophagy. Here we evaluate the effects of pantoprazole to modify cytotoxicity of the anticancer drug docetaxel, and underl...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Br J Cancer
Main Authors: Tan, Q, Joshua, A M, Saggar, J K, Yu, M, Wang, M, Kanga, N, Zhang, J Y, Chen, X, Wouters, B G, Tannock, I F
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Translational Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453951/
https://ncbi.nlm.nih.gov/pubmed/25647012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.17
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker