Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy

BACKGROUND: Autophagy allows recycling of cellular components and may facilitate cell survival after chemotherapy. Pantoprazole inhibits proton pumps and is reported to inhibit autophagy. Here we evaluate the effects of pantoprazole to modify cytotoxicity of the anticancer drug docetaxel, and underl...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Br J Cancer
Glavni autori: Tan, Q, Joshua, A M, Saggar, J K, Yu, M, Wang, M, Kanga, N, Zhang, J Y, Chen, X, Wouters, B G, Tannock, I F
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Translational Therapeutics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453951/
https://ncbi.nlm.nih.gov/pubmed/25647012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.17
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items